高通量血液透析對糖尿病腎病血液透析患者預后影響分析

周晶

[摘要] 目的 分析糖尿病腎病血液透析患者應用高通量血液透析治療的預后影響。 方法 選取該院自2015年10月—2016年10月收治的36例糖尿病腎病血液透析患者作為觀察對象，隨機分為兩組，18例觀察組患者給予高通量血液透析治療，18例對照組患者給予低通量血液透析治療。觀察兩組患者的心腦血管不良事件的發生率，對比兩組患者治療后1年、3年的生存情況。 結果 觀察組患者不良事件發生率27.8%，對照組患者不良事件發生率38.9%（χ2=3.568，P<0.05）。觀察組1年生存率83.3%及3年生存率72.2%，明顯優于對照組的77.8%和44.4%（χ21=5.214，χ22=4.523，P<0.05）。 結論 高通量血液透析對糖尿病腎病血液透析患者預后效果好，可有效降低患者的心、腦血不良事件發生率，改善了患者的生存質量。

[關鍵詞] 糖尿病腎病血液透析;高通量血液透析;預后影響

[中圖分類號] R587.1? ? ? ? ? [文獻標識碼] A? ? ? ? ? [文章編號] 1672-4062（2020）02（b）-0188-03

[Abstract] Objective To analyze the prognostic effects of high-throughput hemodialysis in patients with diabetic nephropathy and hemodialysis. Methods 36 patients with diabetic nephropathy and hemodialysis treated in our hospital from October 2015 to October 2016 were selected as observation objects and randomly divided into two groups. 18 patients in the observation group were given high-throughput hemodialysis treatment. 18 patients in the control group were given low-flux hemodialysis. The incidence of cardiovascular and cerebrovascular adverse events in the two groups of patients was observed， and the survival of the patients in the two groups after 1 year and 3 years of treatment was compared. Results The incidence of adverse events was 27.8% in the observation group and 38.9% in the control group（χ2=3.568， P<0.05）. The one-year survival rate of the observation group was 83.3% and the three-year survival rate was 72.2%， which were significantly better than the 77.8% and 44.4% of the control group（χ21=5.214， χ22=4.523， P<0.05） Conclusion High-throughput hemodialysis has a good prognosis for patients with diabetic nephropathy and hemodialysis. It can effectively reduce the incidence of adverse events of heart and brain blood and improve the quality of life of patients.

[Key words] Diabetic nephropathy hemodialysis; High-throughput hemodialysis; Prognostic effect

隨人們飲食結構的改變、生活水平的提高，糖尿病的發病率正逐年升高。糖尿病患者的發病原因與遺傳、環境因素有關[1]。隨著糖尿病患者數量的增加，也增了其并發癥糖尿病腎病的發病幾率[2]。終末期糖尿病患者，極易出現腎衰竭情況，發生胰島素抵抗等現象，嚴重影響了患者的生理功能，病情嚴重時，甚至危及患者生命[3]。治療糖尿病腎病患者，臨床多采用血液透析，血液透析主要包括高通量血液透析與低通量血液兩種方式[4]。高通量血液透析可有效清除患者的大中分子物質，既節省醫療成本，又能有效降低患者不良事件的發生率[5]。為有效挽救患者生命，該文2015年10月—2016年10月選取該院36例糖尿病腎病血液透析患者進行研究，現報道如下。

1? 資料與方法

1.1? 一般資料

選取該院收治的36例DN血液透析患者作為觀察對象，隨機分為兩組，觀察組18例患者接受高通量血液透析治療，對照組18例患者接受低通量血液透析治療?！?br>