

[摘要] 目的 觀察分析奧美拉唑三聯療法對胃潰瘍復發患者的臨床治療效果以及遠期的復發率。 方法 將筆者所在醫院2009年1月~2011年1月收治的66例胃潰瘍復發患者隨機的分為對照組與實驗組兩組,對照組患者采取阿莫西林、法莫替丁與甲氧氯普胺進行治療,實驗組患者采取阿莫西林、甲氧氯普胺與奧美拉唑進行治療,以4周為1個療程,分析比較兩組患者的臨床療效與不良反應等。 結果 治療4周之后,實驗組患者的臨床效果明顯好于對照組,復發率比對照組明顯要低,差異具有統計學意義(P<0.05)。 結論 阿莫西林、奧美拉唑與甲氧氯普胺三聯療法可以有效治療胃潰瘍復發,療效肯定,復發率低,是值得在臨床上推廣應用開來的。
[關鍵詞] 奧美拉唑;阿莫西林;甲氧氯普胺;法莫替丁;胃潰瘍復發
[中圖分類號] R696 [文獻標識碼] B [文章編號] 2095-0616(2012)21-81-02
Clinical analysis of omeprazole triple therapy in the treatment of 66 cases with gastric ulcer recurrence
WU Chunjie
Medical Department, Shulan City Pingan Center Community Hospital of Jilin Province, Shulan 132605, China
[Abstract] Objective To observe and analyze clinical effect and long-term recurrence rate of omeprazole triple therapy in the treatment of gastric ulcer recurrence. Methods 66 patients with gastric ulcer recurrence in author's hospital from January 2009 to January 2011 were selected and randomly divided into experiment group and control group, the control group was treated by amoxicillin, famotidine and metoclopramide, the experiment group was treated by amoxicillin, metoclopramide and omeprazole. Four weeks as a course, the clinical effect and adverse reactions of the two groups were analyzed and compared. Results After four weeks, the clinical effect of the experiment was obviously better than the control group, and the recurrence rate was lower than the control group(P<0.05), it had statistically significant. Conclusion It's effective and low recurrence rate of amoxicillin, metoclopramide and omeprazole triple therapy in the treatment of gastric ulcer recurrence, is worthy of clinical application.
[Key words] Omeprazole;Amoxicillin;Metoclopramide;Famotidine;Gastric ulcer recurrence
胃潰瘍是一種常見的消化系統疾病,發病率非常高,容易在春冬兩季發病。胃潰瘍的發病原因是多種多樣的,與飲食不規律、吸煙、外界壓力等諸多因素有關,男性發病率明顯高于女性[1]。胃潰瘍容易反復發作,對患者所產生的危害是非常大的,就當前來說,阿莫西林、奧美拉唑與甲氧氯普胺三聯療法治療胃潰瘍反復發作所取得的效果還是比較不錯的。筆者對阿莫西林、奧美拉唑與甲氧氯普胺三聯療法治療胃潰瘍的臨床療效與復發情況做了相關研究,現將結果做如下報告。
1 資料與方法
1.1 一般資料
選擇筆者所在醫院2009年1月~2011年1月收治的66例胃潰瘍復發患者作為此次實驗的研究對象,66例患者均符合胃潰瘍的診斷標準。……