UVB聯(lián)合泛昔洛韋片治療帶狀皰疹療效觀察

任麗萍

[摘要] 目的 觀察UVB聯(lián)合泛昔洛韋片治療帶狀皰疹的療效。 方法 將80例患者按就診順序隨機(jī)分為兩組。治療組40例，采用UVB照射同時(shí)口服泛昔洛韋片；對照組40例，單用泛昔洛韋片口服。兩組均連續(xù)治療1周。結(jié)果 治療組有效率為87.50%，對照組有效率為62.50%，兩組差異有統(tǒng)計(jì)學(xué)意義（χ2=6.67，P<0.01）。治療組止皰、止痛、結(jié)痂時(shí)間及總病程均明顯短于對照組（P<0.01）。兩組均無明顯不良反應(yīng)發(fā)生。 結(jié)論 UVB聯(lián)合泛昔洛韋片治療帶狀皰疹安全有效。

[關(guān)鍵詞] 帶狀皰疹；UVB；泛昔洛韋片

[中圖分類號(hào)] R752.12 [文獻(xiàn)標(biāo)識(shí)碼] B [文章編號(hào)] 1673-9701（2014）02-0156-02

Clinical observation on curative effects of UVB combined with famciclovir tablets in the treatment of herpes zoster

REN Liping

Department of Dermatology， the Central Hospital of Fushun， Fushun113006， China

[Abstract] Objective To observe the efficacy of UVB combined with Famciclovir tablets in the treatment of herpes zoster. Methods A total of 80 cases were randomly divided into two groups. the treatment group was treated with a combination of UVB and famciclovir tablets， and the control group was treated with famciclovir tablets alone. The treatment period was a week. Results The effective rate of the treatment group was 87.50%， and the control group was 62.50%. The difference between the two groups was significant （χ2=6.67， P<0.01）. Times required for blister disappearing， reduced pain， scab forming and the duration of disease in the treatment group were obviously shorter than the control group （P<0.01）. Furthermore， both of two groups showed no adverse events. Conclusion Treatment effect of UVB combined with famciclovir tablets in the treatment of herpes zoster is significant and safe.

[Key words] Herpes zoster； UVB； Famciclovir tablets

帶狀皰疹是臨床常見的病毒性疾病。雖有自限性，但因其有一定病程且常伴程度不等的神經(jīng)痛，甚至遺留后遺癥而影響患者的生活質(zhì)量，所以患者多積極要求治療。本文選擇2012年3月～2013年3月期間我院部分患者采用UVB聯(lián)合泛昔洛韋片的方法治療帶狀皰疹，取得了較好療效，現(xiàn)報(bào)道如下。

1資料與方法

1.1臨床資料

80例患者均來自我院皮膚科門診，均具有典型的臨床表現(xiàn)，符合帶狀皰疹的臨床診斷[1]。其中男38例，女42例；年齡15～75歲；就診時(shí)病程均在1周之內(nèi)。將所有患者按就診順序隨機(jī)分為兩組：治療組40例，發(fā)病部位主要有：三叉神經(jīng)支配區(qū)域4例，頸部神經(jīng)支配區(qū)域5例，肋間神經(jīng)支配區(qū)域25例，腰骶神經(jīng)支配區(qū)域6例；對照組40例，發(fā)病部位主要有：三叉神經(jīng)支配區(qū)域3例，頸部神經(jīng)支配區(qū)域6例，肋間神經(jīng)支配區(qū)域26例，腰骶神經(jīng)支配區(qū)域5例。兩組患者的年齡、性別、病程、病情嚴(yán)重程度比較，差異均無顯著性。排除標(biāo)準(zhǔn)：嚴(yán)重的心肺、肝腎疾病；發(fā)病前1周及發(fā)病時(shí)使用過抗病毒藥物；局部合并有嚴(yán)重細(xì)菌感染者及對所用藥物過敏者；有青光眼、白內(nèi)障、光敏史者；……