70例嗜酸性細胞增多性皮炎患者臨床研究

郭穎

[摘要] 目的 探究嗜酸性細胞增多性皮炎患者的臨床特點。方法 隨機選取該院收治的70例嗜酸性細胞增多增多綜合征作為研究對象，將其納入該研究的觀察組；另外35例健康體檢者作為對照組，對兩組入選病例的臨床資料、實驗室檢查結果及臨床表現進行統計分析，做好相關記錄。結果 比較兩組性別、年齡差異無統計學意義（P>0.05）；觀察組皮膚損害系數、低蛋白血癥、血沉增快、肝臟增大、脾臟增大發生率高于對照組，外周血白細胞的數量多于對照組（P<0.05）。觀察組患者經臨床治療后，均康復出院。結論 嗜酸性細胞增多性皮炎好發于老年男性患者，患者的首發癥狀均為瘙癢性皮炎，隨著病情進展，患者可見紅色斑點、皰疹、出血、結痂等癥狀。盡早分析嗜酸性細胞產生的外部及內部因素，對于遏制病情及制定有針對性的方法具有重要的意義。

[關鍵詞] 嗜酸性細胞增多性皮炎；患者；臨床研究

[中圖分類號] R758 [文獻標識碼] A [文章編號] 1674-0742（2015）04（c）-0026-02

[Abstract] Objective To explore the 70 cases of eosinophilia of the clinical features of patients with dermatitis. Methods Selected an increase of 70 cases in our hospital hypereosinophilic syndrome as research subjects， and included in the present study observation group； another 35 healthy subjects as the control group， two groups of selected cases of clinical data， laboratory test results and clinical manifestations of statistical analysis， make relevant records. Results Compared the gender， age of the two groups， the differences were not statistically significant（P> 0.05）； skin damage factor， hypoalbuminemia， ESR， increased liver， spleen increased incidence of the observation group was higher than that of the control group， the number of peripheral blood leukocytes was more than that of the control group（P<0.05）. The clinical observation of patients after treatment， were discharged. Conclusion Hypereosinophilic dermatitis occurs in older male patients， the first symptom of the patient are itching dermatitis， as the disease progresses， patients can see red spots， sores， bleeding， crusting and other symptoms. Early analysis of external and internal factors produced by eosinophils， for curbing the disease and to develop targeted approach has important significance.

[Key words] Hypereosinophilic dermatitis； Patients； Clinical study

嗜酸性細胞增多性皮炎是由不同的異質性細胞增多產生的一種疾病，嗜酸性細胞增多性皮炎在診斷的時候不容易發現病因，會因為不能正確地分析出發病機制，導致誤診的問題[1]。為探究嗜酸性細胞增多性皮炎患者的臨床特點，該院把收治的70例患有嗜酸性細胞增多性皮炎的病人進行探究，現報道如下。

1 資料與方法

1.1 一般資料

隨機選取在該院治療的70例患有嗜酸性細胞增多性皮炎患者，將其納入該研究的觀察組；另外35例健康體檢者作為對照組，觀察組患者均符合嗜酸性粒細胞增多診斷的診斷標準：骨髓中嗜酸性粒細胞增多、皮膚與內臟受累證據，臨床表現為皮膚癥；外周血嗜酸性粒細胞明顯增加，絕對計數超過1500×10/L，持續時間超過6個月；除外嗜酸性粒細胞增多的其他疾病；患者體內的器官受到不良的影響。