[摘要] 目的 探究短期應用甲強龍治療慢性阻塞性肺疾病的臨床治療效果。方法 方便選擇2013年7月—2015年12月該院收治的40例慢性阻塞性肺部疾病患者為研究對象,將其分為兩組,每組20例,對照組實施常規治療,觀察組以此為基礎,短期使用甲強龍治療,對比治療結果。結果 對照組患者治療有效率為 65.00%,觀察組為90.00%。組間數據差異有統計學意義,P<0.05。和對照組相比,觀察組喘息緩解時間和咳嗽消失時間以及肺部濕啰音消失時間分別為(4.52±1.32)d、(5.26±1.47)d、(5.53±1.29)d,對照組為(5.84±1.78)d、(7.36±1.52)d、(7.55±1.47)d,P<0.05。觀察組ICU住院時間與無創呼吸機輔助通氣時間分別為(4.29±2.63)d、(79.62±32.14)h,對照組為(7.89±3.66)d、(100.36±34.87)h,P<0.05。 結論 對于慢性阻塞性肺部疾病急性期患者,使用甲強龍加以治療,可以快速緩解患者臨床體征,縮短癥狀緩解時間,安全性強,值得進一步在臨床治療中推廣使用。
[關鍵詞] 甲強龍;慢性阻塞性肺疾病;急性期
[中圖分類號] R563 [文獻標識碼] A [文章編號] 1674-0742(2016)12(b)-0118-03
Application Methylprednisolone Short-term Curative Effect Observation of the Treatment of Chronic Obstructive Pulmonary Disease
XU Zhi-ping1,XU Dong2
1.General Medicine, The First People's Hospital of Kunshan, Kunshan, Jiangsu Province, 215000 China;2.Respiratory Medicine, Chinese Medicine Hospital of Yixing, Yixing, Jiangsu Province, 214200 China
[Abstract] Objective To explore the short-term application of methylprednisolone in the treatment of chronic obstructive pulmonary disease treatment effect. Methods Convenient choose July 2013 to December 2015, our hospital of 40 cases of patients with chronic obstructive pulmonary disease as the research object, it can be divided into two groups, 20 cases in each group, control group routine therapy, observation group on this basis, the short-term use of methylprednisolone therapy. Comparing the treatment results. Results Control group patients treatment effective rate was 65.00%, the observation group was 90.00%. Data statistical differences between groups, P < 0.05. Observation group breathing ease and cough disappeared time and lung wet then disappear time respectively(4.52 ±1.32) d,(5.26 ±1.47)d, (5.53 ± 1.29)d, the control group (5.84 ±1.78)d,(7.36 ± 1.52)d,(7.55± 1.47)d, P < 0.05. Observation group ICU length of hospital stay and noninvasive ventilator assisted ventilation time, respectively (4.29 ± 2.63)d, (79.62±32.14)h, control group is (7.89 ±3.66)d,(100.36 ± 34.87)h,(P < 0.05).Conclusion For patients with chronic obstructive lung disease acute stage, using the methylprednisolone therapy, can quickly relieve the clinical symptoms, shortening the time of symptoms, strong security, deserves further used in clinical treatment.
[Key words] Methylprednisolone; Chronic obstructive pulmonary disease; The acute phase
慢性阻塞性肺部疾病(COPD)為臨床常見病,多發病[1]。該疾病的病死率位居相關疾病前列,該疾病的發生和肺部對煙霧等有害氣體或者微塵異常反應存在關聯性,對于COPD,臨床上推崇使用糖皮質激素加以治療[2]。其對于緩解氣流阻塞性氣道炎癥有著相對滿意的治療效果,可在一定程度上延緩疾病惡化速度。甲強龍為新型合成類糖皮質激素的一種,其有著臨床效果好,見效快等特征。為了全面探究短期應用甲強龍治療慢性阻塞性肺疾病的療效,結合實際情況,該文方便選擇2013年7月—2015年12月該院收治的40例該疾病患者為研究對象,并對部分患者使用甲強龍加以治療,得出滿意效果,現報道如下。……