補陽還五湯聯合胞磷膽堿膠囊治療氣虛血瘀型腦梗死后血管性癡呆臨床效果分析

[摘要] 目的 分析中西醫結合治療氣虛血瘀型腦梗死后血管性癡呆臨床效果。方法 方便選取2015年10月—2016年10月在莆田平民醫院與莆田市第一醫院就診98例氣虛血瘀型腦梗死后血管性癡呆患者，隨機分為對照組和實驗組，每組49例患者；對照組口服胞磷膽堿膠囊治療，實驗組在對照組治療基礎上，聯合中藥湯劑治療；對比分析兩組中醫癥候積分、MMSE、ADL得分和臨床治療效果。結果 在治療前兩組中醫癥候積分差異無統計學意義（P>0.05）；在治療后，對照組與實驗組中醫癥候積分分別為（43.58±2.63）分和（33.23±2.65）分。在治療前MMSE評分和ADL評分兩組之間差異無統計學意義（P>0.05）；治療后，實驗組MMSE評分為（25.78±2.9）分，ADL評分為（85.74±7.04）分；均顯著的高于對照組評分（P<0.05）。對照組中，有12例無效，有37例有效和顯效，有效率為75.51%；實驗組中，有7例無效，有42例有效和顯效，有效率為85.71%；實驗組有效率顯著的高于對照組，差異有統計學意義（P<0.05）。結論 中西醫結合治療腦梗死后血管性癡呆，可以顯著的提高患者的精神狀況和生活質量，臨床治療效果較好，在臨床中具有推廣和應用價值。

[關鍵詞] 中西醫結合；腦梗死后血管性癡呆；精神狀況；生活質量

[中圖分類號] R27 [文獻標識碼] A [文章編號] 1674-0742（2016）12（b）-0007-04

Clinical Effect of Buyang Huanwu Decoction Combined with Citicoline Capsule on Vascular Dementia after Cerebral Infarction of Qi Deficiency and Blood Stasis Type

WANG Jin-shu1，HUANG Zhi-xiong2

1.Department of Neurology， Putian People 's Hospital， Putian，Fujian Province，351117 China；2. Department of Traditional Chinese Medicine of Putian First Hospital， Putian， Fujian Province，351100 China

[Abstract] Objective To analyze the clinical effect of integrated traditional Chinese and western medicine on vascular dementia after cerebral infarction with Qi deficiency and blood stasis type. Methods Convenient from October 2015 to October 2016 in our hospital 98 patients with vascular dementia after Qi deficiency and blood stasis cerebral infarction were randomly divided into control group and experimental group， each group of 49 patients； the control group orally The study group was treated with the traditional Chinese medicine decoction on the basis of the control group. The TCM syndrome score， MMSE， ADL score and clinical treatment effect were compared and analyzed. Results There was no significant difference in TCM syndrome scores between the two groups before treatment（P> 0.05）. After treatment， the scores of TCM symptoms in the control group and the experimental group were（43.58 ± 2.63）points and （33.23 ± 2.65）points， respectively. There was no significant difference between the MMSE and ADL scores before treatment（P> 0.05）. After treatment， the MMSE score of the experimental group was（25.78 ± 2.9）points and the ADL score was（85.74 ± 7.04）points Significantly higher than the control group score（P <0.05）. In the control group， 12 cases were ineffective， 37 cases were effective and markedly effective， the effective rate was 75.51%； in the experimental group， 7 cases were ineffective， 42 cases were effective and markedly effective， the effective rate was 85.71%； the experimental group， Which was higher than that in the control group.the difference statistically significant（P <0.05）. Conclusion Integrative Chinese and western medicine treatment of vascular dementia after cerebral infarction， can significantly improve the mental state of life and quality of life， clinical treatment is better， in the clinical application and promotion.

[Key words] Integrative Medicine； Vascular Dementia after Cerebral Infarction； Mental Status； Quality of Life

癡呆為不伴意識障礙但腦皮層高級功能產生獲得性障礙，在臨床中癡呆分混合型癡呆、血管性癡呆、阿爾茨海默癡呆等類型[1]；血管性癡呆常發生在腦梗死后，腦梗死導致患者腦功能衰弱、腦血液循環障礙、腦實質受損等，從而出現認知功能障礙[2]。隨著我國老齡化現象日趨嚴重，由此引發血管性癡呆人數逐漸上升，對患者生活質量和身心健康造成嚴重影響，也給家庭和社會帶來很大負擔[3-4]；……