宮腹腔鏡聯合輔助生殖技術治療輸卵管性不孕患者的臨床療效及安全性

孫瑾+陸子陽

【摘要】目的：探究與分析宮腹腔鏡聯合輔助生殖技術治療輸卵管性不孕患者的臨床療效及安全性。方法：選取我院自2013年8月至2015年8月収治的90例輸卵管性不孕患者，采取隨機數字表法分為對照組與觀察組，每組各45例，對照組給予宮腹腔鏡手術治療，觀察組在其基礎上聯合輔助生殖技術治療，對比兩組患者輸卵管再通率、1周內性生活頻率、并發癥發生率及隨訪2年的妊娠率。結果：對照組與觀察組壺腹部及傘端梗阻、峽部梗阻及間質部梗阻率及再通率相比均無明顯差異（P>0.05）。觀察組較對照組相比1周內性生活頻率、1年內妊娠率、2年內妊娠率均明顯提高，具有統計學意義（P<0.05）。對照組與觀察組術后疼痛、宮內感染及輸卵管穿孔發病率均無明顯差異（P>0.05）。結論：采用宮腹腔鏡聯合輔助生殖技術治療輸卵管性不孕患者的臨床療效顯著，有效提高輸卵管再通率，降低并發癥發生率，安全性較高，增加了性生活頻率、隨訪2年可獲得更高的妊娠率，值得推廣。

【關鍵詞】宮腔鏡；腹腔鏡；輔助生殖技術；輸卵管性不孕；療效；安全性

【Abstract】Objectives： To explore and analyze the clinical efficacy and safety of laparoscopic assisted reproductive technology in treatment of tubal infertility. Methods： 90 patients with oviduct infertility treated in our hospital from August 2013 to August 2015 were selected and randomly divided into control group and observation group， 45 cases in each group. Control group was given palace laparoscopic surgery， while， on such basis， observation group was jointly given assisted reproductive technology treatment. The recanalization rate of fallopian tube， frequency of sex life within a week， the rate of complications and pregnancy rate were followed up for 2 years and compared. Results： Difference in recanalization rate of periampullary and umbrella obstruction， isthmus obstruction and interstitial obstruction rate was not significant between the two groups （P> 0.05）. The frequency of sex life within a week， pregnancy rate within a year and 2 years in observation group was significantly improved compared to control group， with statistical significance （P< 0.05）. Difference in postoperative pain， intrauterine infection and incidence of fallopian tube perforation was not significant （P> 0.05）. Conclusion： The palace of laparoscopic assisted reproductive technology is effective in the treatment of tubal infertile patients， with lower incidence of complications， high safety， and higher pregnancy rate in the 2-year follow-up， which is worthy of promotion.

【Key words】Hysteroscopy； Laparoscope； Assisted reproductive technology； Oviduct infertility； Curative effect； Safety

【中圖分類號】R711.6【文獻標志碼】A

據調查研究資料顯示， 輸卵管性不孕占全部女性不孕的15%～50%，且呈逐年上升趨勢，近年來，隨著宮腔鏡及腹腔鏡技術的不斷發展，使得輸卵管性妊娠的臨床診治得到了廣泛的應用，且具有創傷小，術后恢復快等優勢，但部分患者術后妊娠率仍無法達到滿意目的[1]。現我院于宮腹腔鏡治療輸卵管性不孕的基礎上聯合輔助生殖技術治療，結果總結報告如下。

1資料與方法

1.1一般資料

選取我……