撒莉恒 劉秀麗 宋紹碧
【摘要】 目的:探討硝苯地平治療妊娠期高血壓疾病的臨床效果。方法:選擇筆者所在醫院收治的120例妊娠期高血壓疾病患者,隨機分為觀察組和對照組。兩組均給予硫酸鎂治療,觀察組同時給予硝苯地平治療。觀察兩組血壓、血尿素氮、尿酸改變情況,評定治療效果,觀察妊娠并發癥發生情況。結果:觀察組治療后收縮壓、舒張壓、血尿素氮、尿酸均低于對照組治療后,差異有統學意義(P<0.05)。觀察組胎兒窘迫發生率、宮縮乏力發生率、產后出血發生率及新生兒窒息發生率均低于對照組,差異有統計學意義(P<0.05)。觀察組總有效率高于對照組,差異有統計學意義(P<0.05)。結論:硝苯地平治療妊娠期高血壓疾病的臨床效果顯著,值得借鑒。
【關鍵詞】 妊娠期高血壓疾病; 硫酸鎂; 硝苯地平; 妊娠并發癥
doi:10.14033/j.cnki.cfmr.2017.29.094 文獻標識碼 B 文章編號 1674-6805(2017)29-0183-03
Clinical Analysis of Nifedipine in the Treatment of Hypertensive Disorder Complicating Pregnancy/SA Li-heng,LIU Xiu-li,SONG Shao-bi.//Chinese and Foreign Medical Research,2017,15(29):183-185
【Abstract】 Objective:To explore the clinical effect of Nifedipine in the treatment of hypertensive disorder complicating pregnancy.Method:120 patients with pregnancy induced hypertension in our hospital were randomly divided into observation group and control group.Two groups were given Magnesium Sulfate treatment,the observation group was given Nifedipine treatment.The changes of blood pressure,blood urea nitrogen and uric acid in two groups were observed.Result:After treatment,the systolic blood pressure,diastolic blood pressure,blood urea nitrogen and uric acid in the observation group were lower than those in the control group,and the difference was significant(P<0.05).The observation group of the incidence of fetal distress,incidence rate of uterine atony,the incidence of postpartum hemorrhage and rate of neonatal asphyxia were lower than those of the control group,the difference was statistically significant(P<0.05).The total effective rate of the observation group was higher than that of the control group,the difference was statistically significant(P<0.05).Conclusion:The clinical effect of Nifedipine in the treatment of hypertensive disorder complicating pregnancy is significant,it is worth learning.
【Key words】 Hypertensive disorder complicating pregnancy; Magnesium Sulfate; Nifedipine; Pregnancy complications
First-authors address:The Peoples Hospital of Miyi County,Miyi 617200,China
妊娠期高血壓疾病是妊娠過程中常見的并發癥,患者主要表現為血壓升高、蛋白尿、水腫等癥狀,嚴重的患者可出現抽搐或昏迷等,嚴重影響到母嬰安全。及時有效地治療妊娠期高血壓疾病,有效控制此類疾病癥狀,有助于降低母嬰危險性,提高妊娠結局[1-3]。硫酸鎂在妊娠期高血壓疾病治療中較為常用。硝苯地平屬于鈣通道阻滯劑,具有降壓藥理作用。本文選擇筆者所在醫院收治的妊娠期高血壓疾病患者,觀察硝苯地平對此類患者的治療效果,現報告如下。
1 資料與方法
1.1 一般資料
入選的120例妊娠期高血壓疾病患者均為筆者所在醫院2014年11月-2016年11月病例,上述患者符合妊娠期高血壓疾病診斷標準。同時排除合并有嚴重肝功能、腎功能障礙患者。上述患者隨機分為觀察組和對照組,每組60例。兩組患者一般資料比較,差異無統計學意義(P>0.05),具有可比性,見表1。
1.2 方法
兩組患……