急性心肌梗死溶栓和藥物治療的臨床療效分析

[摘要] 目的 觀察急性心肌梗死患者進行溶栓和藥物治療的臨床效果，評價其用藥安全性和臨床應用價值。 方法 選取筆者所在醫(yī)院2010年8月～2011年8月收治的急性心肌梗死患者126例，隨機分為對照組與觀察組，每組各63例，其中對照組患者采用常規(guī)藥物治療，觀察組患者采用溶栓藥物治療，觀察兩組患者臨床療效及急性期心臟事件的發(fā)生情況。 結果 觀察組患者治療后冠狀動脈再通率明顯高于對照組，患者死亡率低于對照組，而出血和心源性休克等并發(fā)癥發(fā)生率低于對照組，兩組比較差異有統(tǒng)計學意義（P<0.05）。 結論 尿激酶靜脈溶栓治療急性心肌梗死效果顯著，可有效促進患者心肌功能的恢復，明顯提高搶救成功率，值得臨床推廣和應用。

[關鍵詞] 急性心肌梗死；溶栓治療；藥物治療

[中圖分類號] R542.2 [文獻標識碼] B [文章編號] 2095-0616（2012）22-197-02

Clinical effect analysis of thrombolytic medication for AMI

WEN Yan

Traditional Chinese Medicine Hospital of Chuxiong State，Chuxiong 675000，China

[Abstract] Objective To analyze the clinical effect of thrombolytic medication for AMI in order to assess its safety and clinical application value. Methods 126 cases of AMI patients were chosen for the research during the time from August 2010 to August 2011 in hospital.63 cases of patients in the contrast group were treated by routine medication for their treatment and the other 63 patients in the treatment group were treated by thrombolytic medication.Compared with the clinical effects and the emergency situation frequency during their treatment. Results The coronary reperfusion of the patients in the treatment group was obviously higher than that of the contrast group and its mortality and complication such as hemorrhage.Cardiac shock was lower than that of contrast group. Conclusion The thrombolytic medication treatment has obviously clinical effect for AMI patients.It can effective promote patients' myocardial function and increase the success rate of rescue.It should be extended.

[Key words] Acute myocardial infarction；Thrombolytic therapy；Drug treatment

急性心肌梗死（acute myocardial infarction，AMI）是臨床內(nèi)科較為常見的危重疾病之一，按照ST段是否抬高分為ST段抬高型和非ST段抬高型，具有較高的病死率，其發(fā)病原因通常為急性血栓的形成致使冠脈管腔被完全堵塞，造成局部心肌血流缺失[1]。因此，盡快挽救缺血心肌，以實現(xiàn)心肌再灌注成為治療急性心肌梗死的重要手段[2]，筆者所在醫(yī)院通過對2010年8月～2011年8月收治的126例急性心肌梗死患者采用溶栓和藥物治療，現(xiàn)報道如下。

1 資料與方法

1.1 一般資料

選取筆者所在醫(yī)院2010年8月～2011年8月收治的急性心肌梗死患者126例，其中男72例，女54例，年齡44～78歲，平均（59.36±4.78）歲，發(fā)生心肌梗死部位分別為：前壁梗死53例，下壁梗死38例，單純側壁梗死21例，后壁梗死14例。……