何惠嬌 盧先卿 蘇慧
【摘要】 目的 探討觀察鹽酸右美托咪定對剖宮產患者椎管內麻醉期間寒戰反應的預防效果。方法 86例剖宮產并接受椎管內麻醉的患者, 根據其臨床是否應用鹽酸右美托咪定分為研究組與對照組, 每組43例。研究組患者在胎兒剖出后給予鹽酸右美托咪定靜脈注射, 對照組患者則在胎兒剖出后給予等量生理鹽水靜脈注射, 觀察比較兩組患者寒戰反應及不良反應發生情況。結果 研究組中93.02%的患者未出現寒戰反應, 明顯高于對照組的76.74%, 差異具有統計學意義(χ2=4.440, P<0.05)。研究組患者的總不良反應發生率(11.63%)明顯低于對照組(30.23%), 差異具有統計學意義(χ2=4.497, P<0.05)。結論 鹽酸右美托咪定可有效預防剖宮產患者椎管內麻醉期間寒戰反應, 且還有助于減少不良反應, 值得臨床進一步推廣應用。
【關鍵詞】 鹽酸右美托咪定;剖宮產;椎管內麻醉;寒戰反應;預防效果
DOI:10.14163/j.cnki.11-5547/r.2017.25.064
【Abstract】 Objective To investigate the preventive effect of dexmedetomidine hydrochloride on shivering reaction during spinal anesthesia in cesarean section. Methods A total of 86 cesarean section patients undergoing spinal anesthesia were divided by whether using dexmedetomidine hydrochloride into research group and control group, with 43 cases in each group. The research group received intravenous administration of dexmedetomidine hydrochloride after dissection, and the control group received intravenous injection of equal volume of saline after dissection. Observation and comparison were made on shivering reaction and adverse reaction in two groups. Results The research group had obviously higher proportion of shivering reaction as 93.02% than 76.74% in the control group, and the difference had statistical significance (χ2=4.440, P<0.05). The research group had obviously lower incidence of total adverse reactions (11.63%) than the control group (30.23%), and the difference had statistical significance (χ2=4.497, P<0.05). Conclusion Dexmedetomidine hydrochloride can effectively prevent shivering reaction during spinal anesthesia in cesarean section, and reduce the occurrence of adverse reactions. It is worthy of further clinical promotion and application.
【Key words】 Dexmedetomidine hydrochloride; Cesarean section; Spinal anesthesia; Shivering reaction; Preventive effect
寒戰反應是術后常見的并發癥之一, 是機體對中心體溫降低的一種生理反應, 會對患者的生理、心理造成不良影響。有研究證實[1], 誘發患者發生寒戰反應的因素主要來源于兩個方面, 即手術因素與麻醉因素。其中麻醉因素是最主要且最常見的誘因之一[2], 因為患者接受麻醉后, 麻醉藥物都會明顯抑制正常的自主體位調節機制, 從而抑制機體體溫調節中樞, 引起體溫下降, 導致寒戰反應的發生。鑒于此, 本研究為進一步預防剖宮產患者椎管內麻醉期間寒戰反應的發生, 將鹽酸右美托咪定應用于臨床, 結果取得了不錯的成效, 現將其具體詳情報告如下。
1 資料與方法
1. 1 一般資料 本研究所選取的86例研究對象均為2016年1~12月在本院行剖宮產并接受椎管內麻醉的患者, 根據其臨床是否應用鹽酸右美托咪定分為研究組與對照組, 每組43例。……