林潤好 方桂容



【摘要】 目的:觀察氧氣霧化吸入對小兒呼吸系統疾病的治療效果。方法:收集筆者所在醫院2018年11月-2019年11月5 000例小兒呼吸系統疾病患者,隨機數字表分為觀察組和對照組,每組2 500例。對照組采用超聲霧化吸入進行治療,觀察組采用氧氣霧化吸入進行治療,比較兩組總有效率、心率及血氧飽和度水平,比較兩組臨床癥狀消失時間。結果:觀察組總有效率為95.2%(2 380/2 500),高于對照組的78.8%
(1 970/2 500),差異有統計學意義(P<0.05)。治療前兩組心率和血氧飽和度比較差異無統計學意義(P>0.05),治療后觀察組心率和血氧飽和度均高于對照組,差異均有統計學意義(P<0.05)。觀察組氣喘消失時間、肺部啰音消失時間和咳嗽消失時間均早于對照組,差異均有統計學意義(P<0.05)。結論:氧氣霧化吸入對小兒呼吸系統疾病的治療效果較好,顯著改善心率和血氧飽和度。
【關鍵詞】 呼吸系統疾病 氧氣霧化吸入 超聲霧化吸入 治療效果
doi:10.14033/j.cnki.cfmr.2020.16.011 文獻標識碼 B 文章編號 1674-6805(2020)16-00-02
Analysis of the Effect of Oxygen Atomized Inhalation on Pediatric Respiratory Diseases/LIN Runhao, FANG Guirong. //Chinese and Foreign Medical Research, 2020, 18(16): -31
[Abstract] Objective: To observe the therapeutic effect of oxygen atomized inhalation on respiratory diseases in children. Method: A total of 5 000 pediatric patients with respiratory diseases from November 2018 to November 2019 were collected. They were divided into observation group and control group by random number table, with 2 500 cases in each group. The control group was treated with ultrasonic atomized inhalation, and the observation group was treated with oxygen atomized inhalation. The total effective rate, heart rate, and blood oxygen saturation were compared between the two groups, the clinical symptom disappearance time of the two groups were compared. Result: The total effective rate in the observation group was 95.2% (2 380/2 500), higher than 78.8% (1 970/2 500) in the control group, the difference was statistically significant (P<0.05). There was no significant difference in heart rate and blood oxygen saturation between the two groups before treatment (P>0.05), after treatment, both heart rate and blood oxygen saturation in the observation group were higher than those in the control group, the differences were statistically significant (P<0.05). The asthma disappearance time, lung murmur disappearance time, and cough disappearance time in the observation group were earlier than those in the control group, the differences were statistically significant (P<0.05). Conclusion: Oxygen atomized inhalation is effective in treating respiratory diseases in children, and it can significantly improve heart rate and blood oxygen saturation.
[Key words] Respiratory disease Oxygen atomized inhalation Ultrasonic atomized inhalation Treatment effect
First-authors address: Huidong County Maternal and Child Health and Family Planning Service Center, Huidong 516300, China
小兒呼吸系統患病率高,病情多樣,發展快速,對患兒的身體健康造成威脅,臨床表現為喘息、咳嗽、呼吸困難和發熱等癥狀[1]。超聲霧化吸入是治療小兒呼吸系統疾病的方法,但是效果不甚理想[2]。近年來氧氣霧化吸入逐漸應用于呼吸系統疾病的治療中[3]。本研究觀察氧氣霧化吸入對小兒呼吸系統疾病的治療效果,具體如下。
1 資料與方法
1.1 一般資料
收集筆者所在醫院2018年11月-2019年11月收治的
5 000例小兒呼吸系統疾病患者。納入標準:(1)年齡<14歲;(2)符合呼吸系統疾病的診斷標準。排除標準:(1)伴有先天性心臟病;(2)拒不配合。隨機數字表分為觀察組和對照組,每組2 500例。觀察組男1 612例,女888例;年齡1~7歲,平均(3.2±0.5)歲;小兒哮喘752例,毛細支氣管炎637例,支氣管肺炎426例,急性喉炎285例,其他呼吸系統疾病400例。對照組男1 539例,女961例;年齡2~7歲,平均(3.3±0.6)歲;小兒哮喘748例,毛細支氣管炎625例,支氣管肺炎413例,急性喉炎276例,其他呼吸系統疾病438例。兩組一般資料比較差異無統計學意義(P>0.05)。患兒家屬簽署知情同意書。
1.2 方法
兩組患者均采用常規治療方法結合對癥支持治療,包括平喘、鎮靜等。對照組使用WH-968超聲霧化器(中國粵華公司生產),患兒連接在噴嘴,超聲霧化時間20 min,吸入特步他林(Draco Lakemedel AB生產,H20030642,規格:2 ml:5 mg)
2.5 mg;布地奈德混懸液(AstraZeneca Pty Ltd生產,H20140475,規格:2 ml:1 mg),1歲患兒0.5 mg/次,>1歲患兒1.0 mg/次;氨溴索(韓美藥品株式會社生產,H20190041,規格:2 ml:15 mg)7.5 mg/次。觀……