周運生



[摘要] 目的 分析調強放療治療鼻咽癌臨床效果及并發癥。方法 隨機選擇2016年5月—2019年5月該院收治鼻咽癌患者100例,按隨機數表分為兩組,對照組50例采用常規放療治療,研究組50例使用調強放療治療,分析兩組效果與并發癥情況。結果 研究組臨床總有效94.00%比對照組78.00%高,差異有統計學意義(χ2=5.316, P<0.05);研究組患者遠期并發癥發生率為12.00%,明顯比對照組30.00%低,差異有統計學意義(χ2=4.882,P<0.05);研究組患者1年生存率94.00%、2年生存率88.00%明顯高于對照組,比較差異有統計學意義(χ2=4.332、4.000,P<0.05)。結論 鼻咽癌患者采用調強放療治療,能提升患者放療效果,改善其預后,還能減少并發癥發生,安全性高。
[關鍵詞] 調強放療;常規放療;鼻咽癌;臨床效果;并發癥
[中圖分類號] R739? ? ? ? ? [文獻標識碼] A? ? ? ? ? [文章編號] 1674-0742(2020)06(b)-0076-03
[Abstract] Objective To analyze the clinical effect and complications of intensity-modulated radiotherapy for nasopharyngeal carcinoma. Methods From May 2016 to May 2019, 100 patients with nasopharyngeal carcinoma were randomly selected in this hospital, and they were divided into two groups according to the random number table. The effects and complications of the two groups were analyzed. Results The total clinical effectiveness of the study group was 94.00% higher than that of the control group, 78.00%, the difference was statistically significant(χ2=5.316, P<0.05); the incidence of long-term complications in the study group was 12.00%, which was significantly lower than the control group 30.00%,the difference was statistically significant(χ2=4.882,P<0.05); The 1-year survival rate of patients in the study group was 94.00%, and the 2-year survival rate was 88.00%, which was significantly higher than that of the control group. The difference was statistically significant (χ2= 4.332, 4.000, P<0.05).Conclusion The use of intensity-modulated radiotherapy for patients with nasopharyngeal carcinoma can improve the patient's radiotherapy effect, improve its prognosis, and reduce the occurrence of complications. It has high safety.
[Key words] Intensity-modulated radiotherapy; Conventional radiotherapy; Nasopharyngeal carcinoma; Clinical effect; Complications
鼻咽癌在臨床耳鼻咽喉科中是一種較為常見惡性腫瘤疾病,其發病率為耳鼻喉惡性腫瘤首位[1]。鼻咽癌發病因素相對復雜,臨床多認為與環境因素、遺傳因素、病毒感染等因素密切相關,由于鼻咽癌患者的病情比較隱匿,臨床易出現誤診或漏診現象,且一旦確診患者病情多發展為晚期,進而導致其錯過了最佳時機[2]。對鼻咽癌疾病患者,臨床主要采用放射治療、手術切除、輔助化療等方案,相關研究發現,對鼻咽癌患者采用常規放療,能有效延緩疾病,但并發癥比較多,效果不甚理想。近年來,調強放療開始被應用于鼻咽癌疾病患者的臨床治療中,為進一步明確其臨床療效,該研究對該院2016年5月—2019年5月收治鼻咽癌100例患者資料分析,現報道如下。
1? 資料與方法
1.1? 一般資料
該研究經醫學倫理會批準,隨機選取在該院診治鼻咽癌100例患者資料,排除標準:嚴重的肝腎疾病者,心理、精神者;按隨機數表分兩組,對照組(50例),女性23例,男性27例;年齡26~73歲,平均年齡(51.34±1.95)歲;原發癌16例,鼻咽癌并皮肌炎18例,隱性鼻咽癌16例。……