多囊卵巢綜合征胰島素抵抗患者飲食控制及藥物干預對近、遠期并發(fā)癥影響的研究

王淑華 黃建會 管宏麗

【摘要】目的：研究關于多囊卵巢綜合征胰島素抵抗患者飲食控制和藥物干預對近、遠期并發(fā)癥造成的相關影響。方法：選取2012年8月至2014年8月期間在我院收治的150例多囊卵巢綜合征胰島素抵抗患者，并隨機將150例患者分成研究組與參照組兩組。研究組患者80例，參照組患者70例。對研究組與參照組的患者進行干預以后，觀察患者體重指標、體溫情況、月經的周期以及內分泌狀態(tài)和卵泡發(fā)育情況。妊娠以后，統(tǒng)計兩組患者的合并糖尿病情況，以及巨大兒的發(fā)病率，并對參照組與研究組患者的代謝性疾病轉歸進行仔細觀察。結果：在經過飲食控制與藥物干預以后，研究組的患者在妊娠期糖尿病以及巨大兒的發(fā)病率上明顯低于參照組，并觀察兩年期間患者的糖尿病以及高血壓的發(fā)病情況研究組具有顯著的較參照組低的結果。結論：多囊卵巢綜合征胰島素抵抗患者飲食控制和藥物干預對近、遠期并發(fā)癥具有重要的影響作用。通過幫助多囊卵巢綜合征胰島素抵抗患者建立起科學健康的飲食習慣，適當?shù)倪\動，并服用胰島素增敏劑，能夠有效的降低并發(fā)癥的發(fā)生率，推動女性患者盡快恢復健康。

【關鍵詞】多囊卵巢綜合征；胰島素抵抗；飲食及藥物干預；并發(fā)癥

Effect of diet control and drug intervention on short and long term complication in patients with polycystic ovary syndrome and insulin resistanceWANG Shuhua1， HUANG Jianhui2， GUAN Hongli1. 1.Department of Obstetrics and Gynecology， Neijiang City Traditional Chinese Medicine Hospital， Neijiang 641000， Sichuan， China； 2.Department of Severe Medicine， Luzhou Hospital of Traditional Chinese Medicine， Luzhou 646000， Sichuan， China

【Abstract】Objectives： To study the effect of diet control and drug intervention on short and long term complications in patients with polycystic ovary syndrome and insulin resistance. Methods： 150 patients with polycystic ovarian comprehensive syndrome with insulin resistance in our hospital from August 2012 to August 2014 were randomly divided into two groups， study group and control group. There were 80 patients in study group and 70 patients in control group. After intervention， body weight index， body temperature， menstrual cycle and endocrine and follicular development of study group and control group were observed. After pregnancy， the incidences of macrosomia and diabetes occurrence were analyzed. Metabolic disease outcome of two groups was observed. Results： After diet control and drug intervention， the incidences of macrosomia and diabetes occurrence in study group were lower than these in control group. Diabetes and hypertension incidences of study group were significant lower than these in control group during two years after the treatment. Conclusion： Effect of diet control and drug intervention on short and long term complication in patients with polycystic ovary syndrome and insulin resistance is important. Establishing scientific and healthy eating habits， suitable exercise and taking insulin sensitizing agent can effectively reduce the incidence of complications and promote female patients recovery.

【Key words】Polycystic ovary syndrome； Insulin resistance； Patients diet and drug intervention； Complications

【中圖分類號】R711.75【文獻標志碼】A

女性群體中常發(fā)生的內分泌紊亂以及糖代謝異常綜合征也叫多囊卵巢綜合征（PCOS）。隨著現(xiàn)代科學的不斷進步與發(fā)展以及醫(yī)療事業(yè)的不斷改革與推新，一些醫(yī)學研究工作者探索出通過控制飲食以及進行藥物干預的方式降低多囊卵巢綜合征胰島素抵抗患者的并發(fā)癥發(fā)生率，并取得了良好的治療效果[1]。……