血液透析治療腎病綜合征急性腎功能衰竭的臨床效果觀察

章慧

摘要：目的 觀察血液透析治療腎病綜合征急性腎功能衰竭的臨床效果。方法 選取我院2013年6月～2015年5月收治的62例腎病綜合征急性腎功能衰竭患者，采用隨機數字表法分為對照組和觀察組。對照組患者采用常規治療，觀察組患者在此基礎上加用血液透析治療。對比兩組患者治療前后血清肌酐、內生肌酐以及尿素氮水平變化情況；并將兩組患者住院時間與并發癥發生率進行比較；出院后對所有患者均進行1年的隨訪，對比1年內兩組患者的死亡率。結果 治療前兩組患者血清肌酐、內生肌酐以及尿素氮水平比較無明顯差異（P<0.05），治療后兩組患者血清肌酐、內生肌酐以及尿素氮水平明顯改善（P<0.05），但觀察組患者的改善情況顯著優于對照組（P<0.05）；且觀察組患者住院時間更短，并發癥發生率更低，與對照組患者相比，差異顯著（P<0.05）；隨訪1年發現，觀察組患者的死亡率明顯低于對照組（P<0.05）。結論 血液透析治療腎病綜合征急性腎功能衰竭臨床效果顯著，可有效改善患者血清肌酐、內生肌酐以及尿素氮等指標水平，有利于縮短住院時間，降低并發癥發生率，且生存率較高，值得在臨床中推廣應用。

關鍵詞：血液透析；腎病綜合征；急性腎功能衰竭；臨床效果

Abstract：Objective To observe the clinical effect of hemodialysis in the treatment of nephrotic syndrome with acute renal failure.Methods 62 cases of nephrotic in our hospital during June 2013～2015 May were integrated patients with acute renal failure were randomly divided into control group and observation group.The control group was treated with conventional therapy，patients in the observation group on the basis of with the treatment of hemodialysis.Serum creatinine before and after treatment were compared between two groups，creatinine and urea nitrogen level changes；and two groups of patients hospitalized time and complications rate were compared；All patients were followed up for 1 year after discharge，compared with 1 year mortality rate.Results Before treatment two serum creatinine，creatinine and urea nitrogen levels were no significant difference（P<0.05），two groups after the treatment，serum creatinine，creatinine and urea nitrogen levels were significantly changed（P<0.05），but the observation group improved significantly better than the control group（P<0.05）；the observation group patients with a shorter hospital stay，the complication rate is lower， compared with the control group，the difference was significant（P<0.05）；1 years of follow-up， patients in the observation group the mortality rate was significantly lower than the control group（P<0.05）.Conclusion The clinical effect of hemodialysis in the treatment of nephrotic syndrome with acute renal failure is significant，which can effectively improve the patients with serum creatinine，creatinine and urea nitrogen levels，can shorten the hospitalization time，reduce the incidence of complications，and the survival rate is high，it is worth in clinical application.

Key words：Hemodialysis；Nephrotic syndrome；Acute renal failure；Clinical effect

腎病綜合征是指各種原因導致的腎小球基膜通透性增加、腎小球濾過率降低等以腎小球病變為特征的癥狀[1]。急性腎功能衰竭是腎內科常見病癥之一，具有起病急、進展快、病情危重、死亡率高等特點[2]。血液透析是臨床中治療腎病的主要方法之一，經長期臨床試驗表明，其治療效果較好。本文將我院收治的62例腎病綜合征急性腎功能衰竭患者作為研究對象，觀察血液透析治療腎病綜合征急性腎功能衰竭的臨床效果，現報告如下。

1資料與方法

1.1一般資料 將我院收治的62例腎病綜合征急性腎功能衰竭患者納入研討范圍，采用隨機數字表法分為對照組31例和觀察組31例。本組患者均符合腎病綜合征急性腎功能衰竭臨床診斷標準[3]；均對本次研究知情，并簽署知情同意書。……