段恒
【摘要】 目的:探討蝶骨嵴腦膜瘤術后遲發性顱內血腫的臨床治療與預后情況。方法:本次研究選取陽新縣人民醫院2015年2月-2018年2月收治32例蝶骨嵴腦膜瘤術后遲發性顱內血腫患者,對相關資料進行回顧性分析,患者均行開顱血腫清除術,觀察其術后療效、治療滿意度情況,并監測兩組患者并發癥發生率及轉歸情況。結果:32例患者均順利完成開顱血腫清除術,術后予以高壓氧干預,肌力恢復良好。療效評估顯示總有效率為90.63%(29/32),治療滿意度為87.50%(28/32),開顱血腫清除術后并發癥發生率為18.75%(6/32),開顱血腫清除術后患者均未見繼發性顱內血腫形成、術后癲癇、遺留神經功能缺損等嚴重并發癥,預后良好。結論:蝶骨嵴腦膜瘤術后遲發性顱內血腫及時行開顱血腫清除術,可有效清除血腫,改善癥狀,療效可靠,預后良好,但需注意做好并發癥監測,及時處理與治療。
【關鍵詞】 蝶骨嵴腦膜瘤術 遲發性顱內血腫 臨床研究
doi:10.14033/j.cnki.cfmr.2020.08.052??文獻標識碼 B??文章編號 1674-6805(2020)08-0-02
Clinical Study of Delayed Intracranial Hematoma in 32 Patients with Sphenoid Ridge Meningioma/DUAN Heng. //Chinese and Foreign Medical Research, 2020, 18(8): -125
[Abstract] Objective: To investigate the clinical treatment and prognosis of delayed intracranial hematoma after sphenoid ridge meningioma operation. Method: In this study, 32 patients with delayed intracranial hematoma after sphenoid ridge meningioma operation were treated in Yangxin County Peoples Hospital from February 2015 to February 2018. The relevant data were analyzed retrospectively. All patients underwent craniotomy for hematoma removal, and their postoperative efficacy and treatment satisfaction were observed, and the incidence and outcome of complications were monitored. Result: All the 32 patients successfully completed the removal of hematoma after craniotomy. After the operation, hyperbaric oxygen intervention was given and the muscle strength recovered well. The results showed that the total effective rate was 90.63% (29/32), the satisfaction rate was 87.50% (28/32), the complication rate was 18.75% (6/32). There were no serious complications such as secondary intracranial hematoma, postoperative epilepsy, left neurological deficit and so on in all the patients after craniotomy. Conclusion: The delayed intracranial hematoma after sphenoid ridge meningioma operation can be removed effectively, the symptoms can be improved, the curative effect is reliable, the prognosis is good, but we should pay attention to the complications monitoring, timely treatment and treatment.
[Key words] Sphenoid ridge meningioma Delayed intracranial hematoma Clinical study
First-authors address: Yangxin County Peoples Hospital, Yangxin 435200, China
蝶骨嵴腦膜瘤(orbitosphenoid meningioma)是腦膜瘤的一種類型,占腦膜瘤總數的13%~19%,是臨床常見的顱底板腦膜瘤類型[1-2]。手術切除是治療蝶骨嵴腦膜瘤的主要方法,但是開顱手術可引起局部血管、組織損傷,同時全身麻醉也可引起血壓波動等情況,因而患者術后易出現顱內血腫形成等并發癥,其中術后遲發性顱內血腫較為常見,目前對于其治療與預后研究逐漸增多[3-5]。術后遲發性顱內血腫的病情進展較快,可迅速引起神經功能異常、腦疝、腦衰竭等不良預后,多數患者需立即實施開顱血腫清除術[6]。為進一步探明蝶骨嵴腦膜瘤術后遲發性顱內血腫的臨床治療與預后情況,本次研究選取本院32例蝶骨嵴腦膜瘤術患者術后遲發性顱內血腫問題進行分析,對患者開顱血腫清除術的效果進行了分析,并追蹤觀察了患者術后并發癥情況,現將相關病例報道如下。
[2] Nordenskjld A C,Bujila R,Aspelin P,et al.頭顱CT檢查后腦膜瘤的患病風險[J].國際醫學放射學雜志,2018,41(1):96.
[3]羅藝,季學兵.多排螺旋CT血管成像在腦膜瘤術前評估中的應用[J].立體定向和功能性神經外科雜志,2017,30(5):284-288.
[4]張杰,高晉健,張德明,等.外科治療以癲癇為主要癥狀的腦膜瘤124例[J].實用醫學雜志,2018,34(3):427-430,449.
[5]楊俊,賴杰,羅云平,等.術前頭部CT血管造影在腦膜瘤治療中的應用[J].廣西醫學,2018,40(13):1431-1433.
[6] Yogendranathan N,Herath H M M T B,Pahalagamage S P,et al.
Electrocardiographic changes mimicking acute coronary syndrome in a large intracranial tumour:A diagnostic dilemma[J].Bmc Cardiovascular Disorders,2017,17(1):91.
[7]方謙昊,朱紅,何瀚志,等.基于卷積神經網絡的腦膜瘤亞型影像自動分級[J].南京師大學報:自然科學版,2018,41(3):22-27.
[8]何亞文,梁亞明,盧偉坤,等.術前栓塞術對24例腦膜瘤的療效評價[J].中國醫藥科學,2016,6(24):201-203.
[9] Huang Y,Wang Z,Han Q.Extracranial-intracranial bypass in medial sphenoid ridge meningioma associated with severe stenosis of the intracranial segments of the internal carotid artery:A case report[J].Medicine,2018,97(24):e11123.
[10]陳健龍,于沛濤.淺析間變性腦膜瘤的治療及預后[J].醫學與哲學(B),2017,38(6):55-57.
[11] Ho W S,Sizdahkhani S,Hao S,et al.LB-100, a novel protein Phosphatase 2A (PP2A) inhibitor,sensitizes malignant meningioma cells to the therapeutic effects of radiation[J].Cancer Letters,2017,415:217-226.
[12]吳勝波,魏婷婷,趙軍,等.術前栓塞輔助治療腦膜瘤效果Meta分析[J].人民軍醫,2017,60(10):979-983.
[13]楊俊,莫鴻忠,賴杰,等.雙源CTA在蝶骨嵴腦膜瘤術前檢查的應用價值[J].腦與神經疾病雜志,2016,24(10):638-642.
(收稿日期:2019-11-20) (本文編輯:何玉勤)
①陽新縣人民醫院 湖北 陽新 435200