加味杏蘇顆粒對慢性阻塞性肺疾病穩(wěn)定期患者肺功能影響的研究

李宗青 宋梅蘭 張玉 王鴻雁 周有麗 楊娜娜 李帆

【摘 要】目的：探討對慢性阻塞性肺疾病穩(wěn)定期患者的治療中采用加味杏蘇顆粒的治療效果。方法：選取2018年1月至2019年6月在我院肺病一科住院的60例慢性阻塞性肺疾病穩(wěn)定期的患者作為觀察對象，采用隨機(jī)數(shù)字表法將上述患者分成觀察組和對照組，各30例。對照組進(jìn)行常規(guī)西藥治療，如舒利迭吸入1月，觀察組使用加味杏蘇顆粒口服治療，比較兩組治療前、治療1個(gè)月、治療2個(gè)月的生活質(zhì)量評分（CAT）、呼吸困難嚴(yán)重程度量化（mMRC）評分以及治療1個(gè)月、治療3個(gè)月的肺功能指標(biāo)。結(jié)果：觀察組肺功能指標(biāo)如呼氣容積、用力肺活量均高于對照組，觀察組治療1個(gè)月、3個(gè)月的CAT評分、mMRC評分均優(yōu)于對照組，P<0.05。結(jié)論：對慢性阻塞性肺疾病穩(wěn)定期患者的臨床治療中，采用中藥加味杏蘇顆粒治療，不僅可以改善患者的呼吸功能和肺部功能，還可提高患者的生活質(zhì)量，療效顯著，值得臨床推廣。

【關(guān)鍵詞】加味杏蘇顆粒;慢性阻塞性肺疾病;穩(wěn)定期;肺功能;血?dú)庵笜?biāo);心率;呼吸頻率

【中圖分類號】R259 【文獻(xiàn)標(biāo)識碼】 B 【文章編號】1002-8714（2020）08-0002-01

【Abstract】 Objective： To explore the therapeutic effect of the treatment of flavored apricot supel in the treatment of patients with the stabilization period of chronic obstructive pulmonary disease. Methods：0 patients with chronic obstructive pulmonary disease were selected from January018 to June019 during the stabilization period of chronic obstructive pulmonary disease in our hospital， and the above-mentioned patients were divided into observation groups and control groups by random numerical table. The control group was treated with conventional Western medicine， such as Shulidi inhalation in January， and the observation group used oral treatment with flavored apricot supel， comparing the quality of life score （CAT） for two groups before treatment， month of treatment， months of treatment， quantitative （mMRC） score of breathing difficulty severity and lung function index for month and months of treatment. Results： The lung function index such as exhalation volume and force lung capacity were higher than that of the control group， and the CAT score and mMRC score of month and months were better than the control group， P.05. Conclusion： In the clinical treatment of patients with the stabilization period of chronic obstructive pulmonary disease， the treatment of Chinese medicine with miso-sucanm can not only improve the patients respiratory function and lung function， but also improve the patients quality of life， which is remarkable and worthy of clinical promotion. Keywords： flavored apricot sume particles; Chronic obstructive pulmonary disease; Stabilization period; lung function; blood gas index; heart rate; respiratory rate

慢性阻塞性肺病（COPD）是一種呼吸科常見的呼吸系統(tǒng)疾病，是一種多發(fā)病，此病的發(fā)生和吸入有害物質(zhì)以及呼吸道的炎癥反應(yīng)有關(guān)，患者較多，病死率較高，家庭、社會(huì)負(fù)擔(dān)較重，已經(jīng)成為一個(gè)重要的公共衛(wèi)生問題，據(jù)世界衛(wèi)生組織（WHO）公布至2020年，COPD將是世界疾病經(jīng)濟(jì)負(fù)擔(dān)的第五位。在我國也是僅次于心腦血管疾病的嚴(yán)重危害大眾身體健康的慢性呼吸系統(tǒng)疾病。在對COPD患者的治療中，通常采取西藥治療，多以平喘、抗炎、化痰治療，部分患者進(jìn)行氧療，經(jīng)濟(jì)負(fù)擔(dān)較重。有研究表明，若采用中醫(yī)辨證治療，可提高治療效果，達(dá)到標(biāo)本兼治的效果。……