季學(xué)綱
【摘要】 目的 探討歸脾湯加減中藥治療老年高血壓病合并抑郁癥的臨床效果, 分析其對(duì)患者血壓和生活質(zhì)量的影響。方法 106例老年高血壓病合并抑郁癥患者, 對(duì)患者進(jìn)行編號(hào), 其中奇數(shù)號(hào)為觀察組, 偶數(shù)號(hào)為對(duì)照組, 每組53例。觀察組采用歸脾湯加減中藥治療, 對(duì)照組采用西藥舍曲林治療。對(duì)比治療效果。結(jié)果 治療前兩組漢密爾頓抑郁量表(HAMD17)評(píng)分、漢密爾頓焦慮量表(HAMA)評(píng)分、收縮壓谷值、舒張壓谷值、生活質(zhì)量評(píng)價(jià)量表(SF-36量表)評(píng)分比較差異均無(wú)統(tǒng)計(jì)學(xué)意義(P>0.05);治療后兩組HAMD17評(píng)分、HAMA評(píng)分、收縮壓谷值、舒張壓谷值、SF-36量表評(píng)分均較治療前改善, 差異均具有統(tǒng)計(jì)學(xué)意義(P<0.05);且治療后觀察組HAMD17評(píng)分(12.37±6.41)分、HAMA評(píng)分(11.43±6.42)分、收縮壓谷值(134.42±11.31)mm Hg(1 mm Hg=0.133 kPa)、舒張壓谷值(78.24±9.45)mm Hg、SF-36量表評(píng)分(75.43±
23.42)分均優(yōu)于對(duì)照組(17.56±6.41)分、(16.32±7.55)分、(146.57±13.43)mm Hg、(88.66±11.66)mm Hg、
(63.64±22.34)分, 差異均具有統(tǒng)計(jì)學(xué)意義(P<0.05)。結(jié)論 采用歸脾湯加減中藥治療老年高血壓病合并抑郁癥患者效果顯著, 有利于改善患者的血壓水平, 提高患者的生活質(zhì)量, 值得臨床推廣。
【關(guān)鍵詞】 高血壓病;抑郁癥;歸脾湯加減;血壓;生活質(zhì)量;老年
DOI:10.14163/j.cnki.11-5547/r.2017.25.070
【Abstract】 Objective To investigate the clinical effect of traditional Chinese medicine of Guipi decoction add and subtract in the treatment of senile hypertension complicated with depression, and analyze its influence on blood pressure and quality of life of patients. Methods A total of 106 senile hypertension and depression patients were all numbered, and odd number as observation group and even number as control group, with 53 cases in each group. Treatment effect in two groups was compared. Results Before treatment, both groups had no statistically significant difference in 17-item Hamilton depression scale (HAMD17) score, Hamilton anxiety scale (HAMA) score, systolic valley value, diastolic pressure valley value and 36-item short form health survey (SF-36 scale) (P>0.05). After treatment, both groups had better HAMD17 score, HAMA score, systolic valley value, diastolic pressure valley value and SF-36 scale than before treatment, and their difference had statistical significance (P<0.05). After treatment, the observation group had HAMD17 score as (12.37±6.41) points, HAMA score as (11.43±6.42) points, systolic valley value as (134.42±11.31) mm Hg (1 mm Hg=0.133 kPa), diastolic pressure valley value as (78.24±9.45) mm Hg and SF-36 scale score as (75.43±23.42) points, which were all better than (17.56±6.41) points, (16.32±7.55) points, (146.57±13.43) mm Hg, (88.66±11.66) mm Hg and (63.64±22.34) points
in the control group, and their difference had statistical significance (P<0.05). Conclusion Traditional Chinese medicine of Guipi decoction add and subtract provides remarkable effect in treating senile hypertension complicated with depression, and it is conducive to improving the patients blood pressure levels and improve the quality of life of patients. So it is worthy of clinical promotion.endprint
【Key words】 Hypertension; Depression; Guipi decoction add and subtract; Blood pressure; Quality of life; Senile
隨著社會(huì)的不斷發(fā)展, 我國(guó)老齡化程度逐漸日益提高, 老年人的數(shù)量不斷增多, 老年高血壓病合并抑郁癥患者的數(shù)量不斷增多, 對(duì)老年人的生活質(zhì)量造成了嚴(yán)重不利的影響, 需要及時(shí)采取有效的方法進(jìn)行治療。本院對(duì)收治的老年高血壓病合并抑郁癥患者實(shí)施歸脾湯加減中藥治療, 取得了良好的效果, 詳細(xì)情況如下。
1 資料與方法
1. 1 一般資料 選擇本院2015年5月~2016年5月收治的老年高血壓病合并抑郁癥患者106例, 對(duì)患者進(jìn)行編號(hào), 其中奇數(shù)號(hào)為觀察組, 偶數(shù)號(hào)為對(duì)照組, 每組53例。對(duì)照組患者中, 男30例, 女23例, 年齡61~88歲, 平均年齡(67.5±8.4)歲;
觀察組患者中, 男28例, 女25例, 年齡60~86歲, 平均年齡(67.8±9.3)歲。兩組患者一般資料比較差異無(wú)統(tǒng)計(jì)學(xué)意義(P>0.05), 具有可比性。……p>