烏魯木齊維吾爾族、哈薩克族、漢族非酒精性脂肪肝的檢出情況及其危險因素分析

李娜+吳建榮+王淑霞

摘要：目的 探討烏魯木齊維吾爾族（維族）、哈薩克族（哈族）、漢族不同民族非酒精性脂肪肝的檢出情況及其相關危險因素分析。方法 對2016年1月～12月在新疆醫科大學第一附屬醫院健康管理中心體檢的維吾爾族（維族）、哈薩克族（哈族）、漢族人群且資料完整10476樣本進行非酒精性脂肪肝的檢查率及其相關危險因素分析。結果 本次總共調查維、漢、哈三民族人數為10476人，維、漢、哈三民族檢出非酒精性脂肪肝的為2782人，非酒精性脂肪肝的檢出率為26.56%，哈族非酒精性脂肪肝檢出率比漢族高1.16倍（OR=1.456，95%CI=1.234～1.652），維吾爾族非酒精性脂肪肝檢出率比漢族高1.52倍（OR=2.139，95%CI=1.874～2.567），尿酸、高甘油三酯為漢族非酒精性脂肪肝的危險因素，體重指數、尿酸、總膽固醇、高甘油三酯、血糖為維吾爾族非酒精性脂肪肝的危險因素，哈族非酒精性脂肪肝的危險因素為體重指數、尿酸、高甘油三酯。結論 維吾爾族非酒精性脂肪肝的檢出率較高，其次為哈薩克族，危險因素體重指數、尿酸、總膽固醇、高甘油三酯、血糖是非酒精性脂肪肝的危險因素。

關鍵詞：非酒精性脂肪肝；檢出率；危險因素

Abstract：Objective To investigate the detection status and related risk factors of nonalcoholic fatty liver in Uygur （Uygur），Kazak（Kazakh）and Han ethnic groups.Methods From January 2016 to December in the Uygur health management center of the First Affiliated Hospital of Xinjiang Medical University medical examination of Uygur（Uygur），Kazak （Kazakh），analysis of Han nationality and complete data of 10476 samples of nonalcoholic fatty liver disease inspection rate and its related risk factors.Results The total number of Uygur，Han and Kazakh minorities was 10476，and 2782 were detected in non-alcoholic fatty liver，and the detection rate of nonalcoholic fatty liver was 26.56%，Kazak prevalence of NAFLD is 1.16 times higher than the Han nationality（OR=1.456，95%CI=1.234～1.652），the detection rate of nonalcoholic fatty liver in Uygur was 1.52 times higher than that of Han nationality（OR=2.139，95%CI=1.874～2.567），uric acid，high triglyceride for the Han nonalcoholic fatty liver risk factors，body mass index，uric acid，total cholesterol，high triglycerides，blood glucose for the Uygur nonalcoholic fatty liver risk factors，the risk factors of Kazakh nonalcoholic fatty liver weight index，uric acid，high triglycerides.Conclusion The detection rate of nonalcoholic fatty liver in Uygur was higher，followed by Kazak，risk factor BMI，uric acid，total cholesterol，high triglyceride and blood glucose were the risk factors of nonalcoholic fatty liver disease.

Key words：Nonalcoholic fatty liver disease；Detection rate；Risk factor

脂肪肝已成為我國僅次于病毒性肝炎第二大肝臟疾病，已被公認為隱匿性肝硬化常見原因且患病率在全球范圍呈上升趨勢，已嚴重危害國人健康[1-2]，但目前多數人對脂肪肝不重視，輕者科無癥狀，重者病情兇猛。脂肪肝屬于可逆性疾病，早期診斷并治療有利于恢復，在新疆地區各民族之間飲食習慣及生活方式不同，研究不同民族的非酒精性脂肪肝檢出率及其相關危險因素對我國健康管理有重要意義。……